MTP Activity Assay Kit Supplied by Roar Biomedical, Inc.
Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL).[1] MTP is also necessary for assembly and secretion of chylomicrons by the intestine.[1] This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.[1][2]
MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).[3]
Compatible with high-throughput handling systems.
Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.
The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λex=465nm/λem=535nm).
Learn more about Roar Assay Kits for Studies in Lipoprotein Metabolism.
