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Coenzyme A (CoA) Assay Kit sufficient
Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP (adenosine triphosphate).[2] CoA plays important roles in many metabolic pathways, including the Tricarboxylic Acid cycle, and the synthesis and oxidation of fatty acids.[8] One of the main functions of CoA is the carrying and transfer of acyl groups.[3] Acylated deriviates, for example Acetyl-CoA, are critical intermediates in many metabolic reactions, particularly fatty acid and carbohydrate metabolism.[4] CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.[5][6][7]
Coenzyme A (CoA) Assay Kit has been used to measure CoA levels.[1]
Compatible with high-throughput handling systems.
Suitable for the measurement of Coenzyme A (CoA) in a variety of biological samples including cell and tissue lysates
The Coenzyme A Assay kit is an easy and convenient assay to measure the CoA level in a variety of biological samples. CoA concentration is determined by an enzymatic assay, which results in a colorimetric (570 nm)/fluorometric (λex = 535 nm/λem = 587 nm) product, proportional to the CoA present. Typical sensitivities of detection for this kit are 0.1-10 nmol of CoA.
