Trimethyl(trifluoromethyl)silane solution 0.5 M in THF

Stock code :367737
Brand :Sigma-Aldrich
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Trimethyl(trifluoromethyl)silane solution 0.5 M in THF

Application

Reactant for:
• Silver-mediated C-H trifluoromethylation of arenes
• Preparation of trifluoromethyl ketone analog of L-arginine having contrasting inhibitory activity against human arginase I and histone deacetylase 8
• Organocatalyzed regio- and enantioselective allylic trifluoromethylation of Morita-Baylis-Hillman adducts
• Palladium-catalyzed oxidative trifluoromethylation of indoles
• Preparation of 5-HT1A antagonists

• Used as difluorocarbene source

Nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.[4]

Packaging

25 mL in Sure/Seal™

5 mL in glass bottle

More detail