Trimethyl(trifluoromethyl)silane solution 0.5 M in THF
Reactant for:
• Silver-mediated C-H trifluoromethylation of arenes
• Preparation of trifluoromethyl ketone analog of L-arginine having contrasting inhibitory activity against human arginase I and histone deacetylase 8
• Organocatalyzed
regio- and enantioselective allylic trifluoromethylation of Morita-Baylis-Hillman adducts
• Palladium-catalyzed oxidative trifluoromethylation of indoles
• Preparation of 5-HT1A antagonists
• Used
as difluorocarbene source
Nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.[4]
25 mL in Sure/Seal™
5 mL in glass bottle