SMC™ Human Interleukin 17F (IL-17F) Immunoassay Kit
Interleukin-17F (IL-17F) is a member of a group of cytokines called the IL-17 family. Other members in the family include IL-17A, IL-17B, IL-17C and IL-17E (IL-17E is also known as IL-45). IL-17F is involved in mediating proinflammatory responses by inducing the production of many other cytokines,chemokines, and prostaglandins from many cell types. The increased expression of chemokines attracts other cells, including neutrophils. IL-17F has many physiological functions, such as airway remodeling. As a result of these roles, the IL-17 family has been linked to many immune/autoimmune related diseases, including rheumatoid arthritis (RA), asthma, allergic responses, lupus, allograft rejection and anti-tumor immunity.
The SMC™ IL-17F Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
The sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Human IL-17F Immunoassay Kit unparalleled performance the quantification of IL-17F in human EDTA plasma and serum.
Used to detect/quantify:IL-17F
IL-17F Coated Beads (V2)
Standard Diluent
IL-17F Detection Antibody (V2)
Assay Buffer
IL-17F Standard
10X Wash Buffer
Elution Buffer B
Buffer D
SMC™ IL-17F (V2) Immunoassay Kit Instructions
Low-end CV% Range: 3-7%|Low-end CV% Average: 5%
SMC is a trademark of Singulex
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
