SMC™ Human Interleukin 15 (IL-15) Immunoassay Kit
Interleukin-15 (IL-15) is a cytokine that bears structural and biological similarities to IL-2, as both cytokines are triggered by the presence of exogenous bacteria and viruses. Unlike IL-2, which is expressed mainly by activated monocytes, IL-15 is constitutively expressed by a variety of tissues and cell types, including macrophages, dendritic cells, osteoclasts and fibroblasts. IL-15 is known to affect the proliferation of T-, B- and natural killer cells, and initiates the up-regulation of the cytokines GM-CSF and TNF-α. The pro-inflammatory properties of IL-15 elicit autoimmune activity and elevated levels of IL-15 have been associated with psoriasis, multiple sclerosis, rheumatoid arthritis and systemic lupus.
The SMC™ Human IL-15 Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
The sensitivity of Single Molecule Counting (SMC™) gives the SMC™ IL-15 Immunoassay Kit unparalleled performance in the quantification of IL-15 in human EDTA plasma and serum.
Used to detect/quantify:IL-15
IL-15 Coated Beads
Standard Diluent
IL-15 Detection Antibody
Assay Buffer
Human IL-15 Standard
SMC™ Human IL-15 Immunoassay Kit Instructions
10X Wash Buffer
Elution Buffer B
Buffer D
Low-end CV% Range: 7 - 16%|Low-end CV% Average: 10%
SMC is a trademark of Singulex
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
